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Title : New Coconut Oil Studies: Antioxidant Effects Protect Liver and Kidneys – Reverses Effects of Chemotherapy
link : New Coconut Oil Studies: Antioxidant Effects Protect Liver and Kidneys – Reverses Effects of Chemotherapy
New Coconut Oil Studies: Antioxidant Effects Protect Liver and Kidneys – Reverses Effects of Chemotherapy
| Health Impact News | Dec 19, 2017 | Brian Shilhavy |
Virgin coconut oil, depending on how it is processed, is much higher in antioxidants than refined mass-produced coconut oils.
It is not surprising that scientists and researchers in Africa are exploring the benefits of coconut oil, which is native to many tropical African countries, after being deceived for many years by western thinking that coconut oil is harmful due to it being a highly saturated fat.
See:
How Africans have been fooled to think coconut oil and other traditional foods from their culture are unhealthy
The United States leads the world in condemning coconut oil as a dietary oil, even though it has been a part of traditional cultures for thousands of years, and the attack against coconut oil continues through the present time here at the end of 2017. See:
War on Coconut Oil: California Companies Attacked to try and Prevent the Sale of Coconut Oil
Virgin Coconut Oil Protects Against Free Radical Damage due to Heated Vegetable Oils
In a study titled Repeatedly heated palm kernel oil induces hyperlipidemia, atherogenic indices and hepatorenal toxicity in rats: Beneficial role of virgin coconut oil supplementation researchers from Ebonyi State University in Nigeria found that virgin coconut oil supplementation had a positive effect on the kidneys and livers of rats who were also fed repeatedly heated palm kernel oil.
From the abstract:
BACKGROUND:
The literature reports that the health benefits of vegetable oil can be deteriorated by repeated heating, which leads to lipid oxidation and the formation of free radicals. Virgin coconut oil (VCO) is emerging as a functional food oil and its health benefits are attributed to its potent polyphenolic compounds. We investigated the beneficial effect of VCO supplementation on lipid profile, liver and kidney markers in rats fed repeatedly heated palm kernel oil (HPO).
METHODS:
Rats were divided into four groups (n = 5). The control group rats were fed with; a normal diet; group 2 rats were fed a 10% VCO supplemented diet; group 3 administered 10 ml HPO/kg b.w. orally; group 4 were fed 10% VCO + 10 ml HPO/kg for 28 days. Subsequently, serum markers of liver damage (ALT, AST, ALP and albumin), kidney damage (urea, creatinine and uric acid), lipid profile and lipid ratios as cardiovascular risk indices were evaluated.
Palm kernel oil, which is different from regular palm oil, is common in Africa.RESULTS:
HPO induced a significant increase in serum markers of liver and kidney damage as well as con- comitant lipid abnormalities and a marked reduction in serum HDL-C. The lipid ratios evaluated for atherogenic and coronary risk indices in rats administered HPO only were remarkably higher than control. It was observed that VCO supplementation attenuated the biochemical alterations, including the indices of cardiovascular risks.
CONCLUSIONS:
VCO supplementation demonstrates beneficial health effects against HPO-induced biochemical alterations in rats. VCO may serve to modulate the adverse effects associated with consumption of repeatedly heated palm kernel oil.
However, this study may offer more useful applications for American diets, since the main dietary oils in the U.S. are the polyunsaturated oils from corn and soy, which are very prone to oxidation and free radical damage when heated. (More on polyunsaturated oils for cooking)
Virgin Coconut Oil to Protect Kidneys from Cancer Chemotherapy Drugs
Another study from Nigeria published in December of 2017 is titled Antioxidant and anti-inflammatory effects of virgin coconut oil supplementation abrogate acute chemotherapy oxidative nephrotoxicity induced by anticancer drug methotrexate in rats.
The researchers looked at antioxidant and anti-inflammatory effect of virgin coconut oil when supplemented with the anti-cancer drug Methotrexate.
From the study’s abstract:
BACKGROUND:
Methotrexate (MTX) is an efficacious anticancer agent constrained in clinical use due to its toxicity on non-targeted tissue, a considerable source of worry to clinicians. Because the toxicity is associated with oxidative stress and inflammation, the study explored antioxidant and anti-inflammatory effect of virgin coconut oil (VCO) supplementation in nephrotoxicity induced by MTX in rats.METHODS:
Rats were randomized into 4 groups (n=6) as follows: Control group; MTX group injected with single dose of MTX (20mg/kg, ip) on day 14; VCO (5%)+MTX and VCO (15%)+MTX groups were pre-treated with VCO diet and injected with single dose of MTX (20mg/kg, ip) on day 14. After 3 days of MTX injection, serum kidney markers, renal activities of antioxidant enzymes and glutathione (GSH) content were determined. Lipid peroxidation level and inflammatory markers- interleukin-6 (IL-6), nitric oxide (NO) and C-reactive protein (CRP) were estimated in kidney. Histopathological alterations were examined for kidney damage.
RESULTS:
MTX nephrotoxicity was evidenced by markedly elevated serum renal markers along with significant decreases in renal GSH and activities of antioxidant enzymes confirmed by histopathology. Lipid peroxidation level, IL-6, NO and CRP markedly increased compared to control. VCO supplementation prior to MTX injection attenuated MTX-induced oxidative nephrotoxicity via prominent increases in GSH and antioxidant enzyme activities in a dose-dependent manner. The renal inflammatory markers and MDA depleted considerably compared to MTX control group. Histopathological alterations were mitigated to confirm the biochemical indices.
CONCLUSION:
VCO supplementation demonstrates nephroprotective activity by attenuating MTX oxidative nephrotoxicity via antioxidant and anti-inflammatory activities in kidney. Our results suggested that VCO may benefit cancer patients on MTX chemotherapy against kidney injury.
About the author: Unlike many people who write about coconut oil by simply reading about it, Brian Shilhavy actually lived in a coconut producing area of the Philippines for several years with his family, observing firsthand the differences between the diet and health of the younger generation and those of his wife’s parents’ generation still consuming a traditional diet. This led to years of studying Philippine nutrition and dietary patterns first hand while living in a rural farming community in the Philippines. Brian is the author of the best-selling book: Virgin Coconut Oil: How it has changed people’s lives and how it can change yours!
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thus Article New Coconut Oil Studies: Antioxidant Effects Protect Liver and Kidneys – Reverses Effects of Chemotherapy
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